青岛大学团队曹玉论文多图与过往至少十篇研究高度重合,或涉数据造假,学术诚信遭严重质疑

学术荟萃2025-05-03 12:30:00山东

Part.1

论文简介


标题:Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4

日期:2021年4月15日

单位与作者青岛大学附属医院 Xin Li、Pingping Li、Yu Cao(音译 曹玉)

期刊:Frontiers in Cell and Developmental Biology


Part.2

图像异常问题


#1 图7J与另外三篇论文出现重复。
Fig 7J.
Clockwise from top:


#2 图 4A、7E。迁移和入侵面板重叠。

#3 图6E和 Fang et al 2014 的图4G出现重复。

[left] Fig 6E.

[right] Fig 4G from "Overexpressed homeobox B9 regulates oncogenic activities by transforming growth factor-b1 in gliomas" (Fang et al 2014).



#4 图3B、E和数十篇论文出现重复。

Fig 3B,E.



Lots of duplications with other papers within this sprawling corpus. Left to right:



Left to right:





Fig 3B of "Aberrant JMJD3 Expression Upregulates Slug to Promote Migration, Invasion, and Stem Cell–Like Behaviors in Hepatocellular Carcinoma" (Tang et al 2016).



[left] Fig 8C from "KDM5B is overexpressed in gastric cancer and is required for gastric cancer cell proliferation and metastasis" (Wang et al 2015).

[right] Fig 5A from Lv et al again.


Clockwise from left:


Fig 7A,B,C,E from "MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway" (Xia et al 2015).

Fig 6B/E from Huo et al again.

Fig 3E from "Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation" (Sun et al 2014).



[left] Fig 3B from "Involvement of CUL4A in Regulation of Multidrug Resistance to P-gp Substrate Drugs in Breast Cancer Cells" (Wang et al 2013).

[right] Fig 5A/C from Lv et al.




#5 图7I和图7E出现重复。

I missed this in Fig 7I.

And this, in Fig 7E.






基金支持:


  • 山东省自然科学基金资助,批准号为ZR2019MH101。





参考信息:

https://pubpeer.com/publications/B732A725DB806C1BEFCC7E2C3722B2#1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082113/