复旦大学附属华山医院北院刘杨、上海市第一妇幼保健院妇科殷怡华论文图像重复泛滥成灾,作者团队如何自证清白?

学术荟萃2025-04-05 18:19:00山东


Part.1

论文简介


标题:Inhibitory effects of Arhgap6 on cervical carcinoma cells

日期:2015年12月1日

单位与作者:复旦大学附属华山医院北院Junping Li、Yang Liu(通讯作者 音译 刘杨)

上海市第一妇幼保健院妇科Yihua Yin(通讯作者 音译 殷怡华)

期刊:Experimental and Therapeutic Medicine

Part.2

图像重复问题



#1 图6b面板重叠,图8a,c面板重叠。





#2 图2e与Zhang et al 2017的5C出现重复。

[left] Fig 2e.
[right] Fig 5C from "FAM46C is critical for the anti-proliferation and pro-apoptotic effects of norcantharidin in hepatocellular carcinoma cells" (Zhang et al 2017).




#3 图9e与Huang et al 2016的图5C出现重复。

[left] Fig 5C from "Effects of UCP4 on the Proliferation and Apoptosis of Chondrocytes: Its Possible Involvement and Regulation in Osteoarthritis" (Huang et al 2016).

[right} Fig 9e.






#4 图9f与Diao et al 2017的图2D、Xu et al 2016的图5D、Ding et al 2016的5C出现重复。

[left] Fig 9f.

[right] Fig 2D from "IQGAP1-siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines" (Diao et al 2017).






[left] Fig 5D from "RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells" (Xu et al 2016).
[right] Fig 5C from "Silencing of SOX12 by shRNA suppresses migration, invasion and proliferation of breast cancer cells" (Ding et al 2016).


#5 图2e与Qin et al 2016的图6A出现重复。

[left] Fig 2e again.


Another sighting! [left] Fig 6A from "Silencing of WWP2 inhibits adhesion, invasion, and migration in liver cancer cells" (Qin et al 2016).



#6 图8C与Zhou et al 2019的图3C出现重复。

Fig 8c.



Fig 3C from "Fibronectin promotes cervical cancer tumorigenesis through activating FAK signaling pathway"(Zhou et al 2019).


#7 图6b与Wan et al 2021的图5B、5C出现重复。

Fig 6b again.


Fig 5B and 5C (H1581 panels) from "LncRNA WT1-AS downregulates lncRNA UCA1 to suppress non-small cell lung cancer and predicts poor survival" (Wan et al 2021).




#8 图9f与Hu et al 2016的图4A出现重复。


[left] Fig 4A, BT474 bands from "RNA Interference of IQ Motif Containing GTPase-Activating Protein 3 (IQGAP3) Inhibits Cell Proliferation and Invasion in Breast Carcinoma Cells" (Hu et al 2016).

[right] Fig 9f again.


#9 图6d与其他三篇论文出现重复。

Clockwise from upper left:

  • Fig 4A,C,E from "ARHGAP1 overexpression inhibits proliferation, migration and invasion of C-33A and SiHa cell lines" (Li et al 2017).

  • Fig 2D from "Long Non-Coding RNA-NEAT1 Promotes Cell Migration and Invasion via Regulating miR-124/NF-κB Pathway in Cervical Cancer" (Shen et al 2020).

  • Fig 3E from "Everolimus inhibits breast cancer cell growth through PI3K/AKT/mTOR signaling pathway" (Du et al 2018).

  • Fig 6d.




#10 图7d与其他三篇论文出现重复。


Clockwise from upper left:

  • Fig 5A,C,E from "ARHGAP1 overexpression inhibits proliferation, migration and invasion of C-33A and SiHa cell lines" (Li et al 2017).
  • Fig 2C from "Long Non-Coding RNA-NEAT1 Promotes Cell Migration and Invasion via Regulating miR-124/NF-κB Pathway in Cervical Cancer" (Shen et al 2020).
  • Fig 3E,F from "Everolimus inhibits breast cancer cell growth through PI3K/AKT/mTOR signaling pathway" (Du et al 2018).
  • Fig 7d.


#11 图2f与 Wu et al 2021 的图5e出现重复。


[left] Fig 2f.

[right] Fig 5e from "TRIM65 Promotes Invasion of Endometrial Stromal Cells by Activating ERK1/2/C-myc Signaling via Ubiquitination of DUSP6" (Wu et al 2021).










#12 图9e 与 Xu et al 2016 的图5C出现重复。
[left] Fig 5C from "RNA interference against TRIM29 inhibits migration and invasion of colorectal cancer cells" (Xu et al 2016).[right] Fig 9e again.






参考信息:

https://pubpeer.com/publications/B69C2B3943CD9ED5D88418F886F1C7#

https://pubmed.ncbi.nlm.nih.gov/26628301/