图2E/F(doi: 10.3892/etm.2019.7841)
主编已撤回本文,因为对本文中展示的图表存在担忧。这些担忧使得文章的整体科学严谨性受到质疑。文章发表后进行的一项调查发现以下问题:
[1]中图6的H716和CO802 D5图板与图1C中的正常组、病例1组和肿瘤、病例1组图板(旋转后)似乎重叠;
[2]中图3B的mir-9-5p mimics control、MKN-45图板与图2E中的Vector、GIST-T1图板(旋转后)似乎重叠;
[3]中图4E的HEC1A、si-TTB-AS1+miR-NC图板与图2E中的Vector、GIST-882图板(旋转后)似乎重叠;
[4]中图3A的第一个图板与图3E中的BRD4图板(旋转后)似乎重叠;
[5]中图4的C和E图板与图4C中的Vector、BRD4和BRD4、BRD4图板(旋转后)似乎重叠;
[5]中图3的24小时、BRAF V600E、24小时、pEGFR和24小时、EGFR图板以及图4的Ischemia、BRAF V600E图板与图7A中的四个图板(旋转后)似乎重叠;
[6]中图3A的第二和第三个图板与图3F中的两个图板(旋转后)似乎重叠。
问题图板代表来自不同实验条件下动物的组织。因此,主编不再相信本文所展示研究的完整性。
作者未回复出版商关于此次撤回的函件。
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参考信息https://www.nature.com/articles/s41419-025-07520-4