2020年6月5日，西安交通大学第一附属医院&西安交通大学在Cancer Cell International(中科院二区 IF=5.3)期刊上在线发表题为"ZKSCAN3 drives tumor metastasis via integrin β4/FAK/AKT mediated epithelial-mesenchymal transition in hepatocellular carcinoma"(ZKSCAN3通过整合素β4/FAK/AKT介导的上皮-间质转化促进肝细胞癌的肿瘤转移)论文。
第一作者：西安交通大学第一附属医院Jieqiong Li, Nan Hao
通讯作者：西安交通大学第一附属医院 Nan Yang(音译 杨楠), 西安交通大学 Xiaomei Li(音译 李小妹)
本研究得到了中国国家自然科学基金（项目编号：81773123，81874069）的资助。#1 Figure 6D Artificial Cells Nanomedicine and Biotechnology (2019) doi: 10.1080/21691401.2019.1670190 https://pubpeer.com/publications/8CDC6E6338DB3908698A528D4296E5Figure 2d Cancer Cell International (2020) doi: 10.1186/s12935-020-01307-7（本文）
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#2 An image in Figure 6C seems to have been previously published in another paper.
Figure 9C: Molecular Cancer (2017), doi: 10.1186/s12943-017-0675-y
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Another overlap, between a different panel of Fig 6C, and 9C of Xu et al (2017). It appears that both groups of authors had access to a single larger image of which both panels are details.
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#3 Elsewhere in Fig 6C, two panels overlap after rotation.
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通讯作者杨楠回应：
感谢读者的评论。经过我们的调查，确认由于外观和文件名相似，我们不小心将另一项目（在同一实验室正在进行中）的图片混入其中。我们对因我们的疏忽给读者带来的任何不便深感抱歉，并对这些无心之失表示诚挚的歉意。我们已经联系期刊方以更正这篇文章。
#4 [above] Fig 6D from "MicroRNA-1301 inhibits migration and invasion of osteosarcoma cells by targeting BCL9" (Wang et al 2018).
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#5 Recycled WBs.
left] Fig 7e from "LncRNA OIP5-AS1 loss-induced microRNA-410 accumulation regulates cell proliferation and apoptosis by targeting KLF10 via activating PTEN/PI3K/AKT pathway in multiple myeloma" (Yang et al 2017).[below] Fig 4F from "MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway" (Xu et al 2017).
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#6 [left] Fig 5a.
[right] Fig 6a from "MicroRNA-1468 promotes tumor progression by activating PPAR-γ-mediated AKT signaling in human hepatocellular carcinoma" (Liu et al 2018) [retracted].
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#7 Left to right:
Fig 5F from "Long noncoding RNA PICSAR/miR‐588/EIF6 axis regulates tumorigenesis of hepatocellular carcinoma by activating PI3K/AKT/mTOR signaling pathway" (Liu et al 2020).Fig 7e from "LncRNA OIP5-AS1 loss-induced microRNA-410 accumulation regulates cell proliferation and apoptosis by targeting KLF10 via activating PTEN/PI3K/AKT pathway in multiple myeloma" (Yang et al 2017).本文已被国家自然科学基金委员会通报（2024年第一批次）： https://www.nsfc.gov.cn/publish/portal0/jd/04/info92362.htm
本文已于2024年11月7日被撤回：
已撤回本文，因为文章发表后注意到图6C已在另一出版物[1]中发表过，且图2D中的图像与另一出版物[2]存在重叠。因此，主编对该文结果的真实性失去了信心。
[1] Xu Q, Liu X, Liu Z, et al. MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway. Mol Cancer. 2017;16:103. https://doi.org/10.1186/s12943-017-0675-y[2] Yao B, Li Y, Wang L, Chen T, Niu Y, Liu Q, Liu Z. MicroRNA-3194-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by decreasing Wnt/β-catenin signaling through targeting BCL9. Artif Cells Nanomed Biotechnol. 2019;47(1);3885–3895. https://doi.org/10.1080/21691401.2019.1670190
参考信息
https://pubpeer.com/publications/3B8DCF5FD243DBE29DE44124726673#10https://pubmed.ncbi.nlm.nih.gov/32518525/https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03566-0任何单位或个人认为本内容可能涉嫌侵犯其合法权益，及时向我们提出书面权利通知及详细侵权情况，我们将会依法尽快移除相关涉嫌侵权的内容。
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