Part.1
论文简介
日期:2019年3月7日
单位与作者:中国中医科学院眼科医院 Weiyi Li、Zefeng Kang(通讯作者 音译 亢泽峰)
期刊:Cellular & Molecular Biology Letters
Part.2
图像重复问题
#1 图4B与 Mao et al 2021 的图7D/E出现重复。
[left] Fig 2a from "Knockdown of ZFR suppresses cell proliferation and invasion of human pancreatic cancer" (Zhao et al 2016).
[right] Fig 2B.
[left] Fig 2C from "MicroRNA-567 inhibits cell proliferation, migration and invasion by targeting FGF5 in osteosarcoma" (Liu et al 2018).
[right] Fig 2D.
[left] Fig 1B. Bands seem to have been sourced from [upper right] Fig 2E of "MiR-375 attenuates injury of cerebral ischemia/reperfusion via targetting Ctgf" (Ou et al 2017);
and [lower right] Fig 1A (Duodenum panel) from "Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments" (Zumbrennen-Bullough et al 2014).
[left] Fig 4A from "Upregulation of T?cadherin suppresses cell proliferation, migration and invasion of gastric cancer in???vitro" (Lin et al 2017).
[right] Fig 4A.
Part.3
撤稿说明
2025年2月7日被撤回:总编辑已撤回本文,原因是本文中的图表存在问题,这些问题使得文章的整体科学性受到质疑。文章发表后进行的调查发现存在以下问题:
图1B中的第二个GAPDH条带似乎与[1]中图2E的GADPH条带重叠;
图1B中的第三个CDKL1条带在翻转并重新缩放后,似乎与[2]中图1A的Ftl1、Duodenum条带重叠;
图2B中siCDKL1组的GFP面板中的显微照片似乎与[3]中图2a的shZFR组的GFP面板中的显微照片重叠;
图2D中的GAPDH条带在翻转并重新缩放后,似乎与[4]中图2C的MG-63组的GADPH条带重叠;
图4A中NC组的0h测定结果似乎与[5]中图4A的pcDNA组的0h测定结果重叠。
因此,总编辑不再相信本文所呈现研究的完整性。作者未回复出版商的函件。
参考文章:
[1] Ou J, Kou L, Liang L, Tang C. MiR-375 attenuates injury of cerebral ischemia/reperfusion via targetting Ctgf. Biosci Rep. 2017;37(6):BSR20171242. https://doi.org/10.1042/BSR20171242.
[2] Zumbrennen-Bullough KB, Becker L, Garrett L, Holter SM, Calzada-Wack J, et al. Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments. PLoS ONE. 2014;9(6):e98072. https://doi.org/10.1371/journal.pone.0098072.
[3] Zhao X, Chen M, Tan J. Knockdown of ZFR suppresses cell proliferation and invasion of human pancreatic cancer. Biol Res. 2016;49:26. https://doi.org/10.1186/s40659-016-0086-3.
[4] Liu D, Zhang C, Li X, et al. MicroRNA-567 inhibits cell proliferation, migration and invasion by targeting FGF5 in osteosarcoma. EXCLI J. 2018;17:102–12. https://doi.org/10.17179/excli2017-932.
[5] Lin J, Chen Z, Huang Z, Chen F, Ye Z, Lin S, Wang W. Upregulation of T-cadherin suppresses cell proliferation, migration and invasion of gastric cancer in vitro. Exp Ther Med. 2017;14:4194–200. https://doi.org/10.3892/etm.2017.5090.
青岛市自主创新计划应用研究基础项目(编号:15–9–1-59-jch)
深圳市医学“三名工程”项目(SZSM201812090)
参考信息:
https://pubpeer.com/publications/9CC2BE6FB810816D46546574DA4B23#6
https://pubmed.ncbi.nlm.nih.gov/30891073/
https://link.springer.com/article/10.1186/s11658-025-00698-7