浙江医院Hang Lin(第一兼通讯)论文被撤稿,蛋白印迹以及病理图面板重复

R2Reviewer 22025-03-07 17:46:31浙江

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论文信息


2019年10月18日,浙江省人民医院骨科的Hang Lin(第一作者&通讯作者 音译 林杭)Biochemistry and Cell Biology(中科院三区 IF=2.4)期刊上在线发表题为"Long noncoding RNA HIF1A-AS2 facilitates cell survival and migration by sponging miR-33b-5p to modulate SIRT6 expression in osteosarcoma"(长非编码 RNA HIF1A-AS2 通过海绵状 miR-33b-5p 调节骨肉瘤中 SIRT6 的表达,促进细胞存活和迁移)的论文。


0这项工作得到了浙江省基础公益研究项目(项目编号:LY18H160045)和浙江省中医药科技项目(项目编号:2018ZB007)的支持。

一家年轻医院的一段传奇:浙江省人民医院做对了什么?-健康界

质疑信息


  • 图3B图像面板重复。

Two images in Figure 3B seem to overlap, but are described differently.


This paper was identified with 'The Clear Skies Papermill Alarm.'



  • 图3C与他文WB印迹重复。

There may also be some overlaps within Figure 3C, and also between Figure 3C and Figure 2f of a BioMed Research International paper.


The cropping of the gel strip images seems tighter in the earlier paper, suggesting that perhaps the involvement of a party who prepared both papers from a larger original image.


Biochemistry and Cell Biology (2020), doi: 10.1139/bcb-2019-0171, discussed here: https://pubpeer.com/publications/5DCCCED0787614A62F955AD9C86F18


BioMed Research International (2021), doi: 10.1155/2021/6622342, discussed here: https://pubpeer.com/publications/3EDC86BCDCE8C5C695BC277A169002




  • 图9a与另一篇包含共同作者文章中的图7A图像面板重复。

In Figure 2E? There seem to be some bands that appear very similar, with only a difference in vertical dimensions.






撤稿原因


本文已于2025年2月26日被撤回:本文因图像重复问题已被撤回。该文章中存在一行凝胶图像完全重复和一个面板部分重复的情况。具体而言:


? 在图4E的“HOS”列中,“Cleaved caspase-3”(裂解的半胱天冬酶-3)行的蛋白条带与该图“Cleaved PARP”(裂解的聚腺苷二磷酸核糖聚合酶)行的蛋白条带完全相同。

? 在图3B的迁移面板“U2OS shRNA-1”的左上角部分,与同一图中“shRNA-1”侵袭面板的左下角部分存在部分重复。


鉴于这些图像问题,主编们对该研究的结论失去了信心,并决定撤回该文章。


此次撤回符合《Biochemistry and Cell Biology》杂志及其出版商加拿大科学出版公司的出版政策。


作者无法联系到以对此撤回声明作出回应。





参考信息

https://pubpeer.com/publications/5DCCCED0787614A62F955AD9C86F18

https://pubmed.ncbi.nlm.nih.gov/31626739/

https://cdnsciencepub.com/doi/full/10.1139/bcb-2025-0019