与9篇论文图像面板重复!吉林大学中日联谊医院Youmao Tao的论文被撤稿

净研行动净研行动2025-03-11 10:34:15浙江
01
问题论文




标题:MicroRNA-216a inhibits the metastasis of gastric cancer cells by targeting JAK2/STAT3-mediated EMT process

期刊:Oncotarget

单位:吉林大学中日联谊医院

发表时间:2017年10月4日

DOI: 10.18632/oncotarget.21488

撤稿原因:文中多幅图片是从先前已发表的论文中重复使用的。




02
具体说明




① 图2B,E和与两篇无关论文图像面板重叠。

图5a(doi: 10.1038/cddis.2014.256)
图4A/B(doi: 10.1186/1476-4598-13-68)
图2B,E(本文)


② 图2C/F与无关论文中(doi: 10.1002/2211-5463.12215)的图2C,3C的面板重叠。

同时图7C与该论文中的图3D的面板重叠。

③ 图2C/F与无关论文中(doi: 10.1186/1476-4598-13-95)的图2C,3C的面板重叠。

④ 图6与无关论文中的WB印迹存在重叠。

图8(doi: 10.18632/oncotarget.21209)

 9A,C(doi: 10.18632/oncotarget.16850)

⑤ 图5C与无关论文中(doi: 10.1007/s13277-016-5444-9)的图6a的WB印迹存在重叠

⑥ 图7A与无关论文中(doi: 10.1186/1476-4598-13-106)的图6B/D的WB印迹存在重叠



⑦ 7B, 8B与无关论文图像面板重叠
图2B,E(doi: 10.3892/or.2017.5781)
7B, 8B(本文)
图4E,F(doi: 10.1186/1476-4598-13-95)




03
处理结果




Oncotarget 已完成对本文的调查,经核实,文中多幅图片是从先前已发表的论文中重复使用的。特别是,图2(B和E面板)以及图7B和图8B中的伤口愈合实验图像是四起不同早期论文[1–4]中伤口愈合实验图像的重复。图2的C和F面板以及图7C和图8C中的Transwell迁移实验图像被发现是另一篇随后也被撤回的早期论文中Transwell迁移实验图像的重复[5]。图4A、5C、6和图7A重复使用了多篇不相关论文[6–8]中的大量蛋白印迹图像,其中一篇随后也被撤回[8]。此外,图6还重复使用了图5C以及同一实验室早期论文中的蛋白印迹图像[9]。我们多次尝试联系作者以获取有关这些重复使用的更多信息,但作者均未予回应。因此,编辑部决定撤回本文。


涉及文章

[1] Sun M, Liu XH, Lu KH, Nie FQ, Xia R, Kong R, Yang JS, Xu TP, Liu YW, Zou YF, Lu BB, Yin R, Zhang EB, et al. EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promotes NSCLC cell proliferation and metastasis by affecting the epithelial-mesenchymal transition. Cell Death Dis. 2014; 5:e1298. https://doi.org/10.1038/cddis.2014.256. [PubMed]

[2]  Sun M, Liu XH, Wang KM, Nie FQ, Kong R, Yang JS, Xia R, Xu TP, Jin FY, Liu ZJ, Chen JF, Zhang EB, De W, Wang ZX. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition. Mol Cancer. 2014; 13:68. https://doi.org/10.1186/1476-4598-13-68. [PubMed]

[3]  Qu Y, Chen Q, Lai X, Zhu C, Chen C, Zhao X, Deng R, Xu M, Yuan H, Wang Y, Yu J, Huang J. SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1. Mol Cancer. 2014; 13:95. https://doi.org/10.1186/1476-4598-13-95. 

[4] Yu DL, Zhang T, Wu K, Li Y, Wang J, Chen J, Li XQ, Peng XG, Wang JN, Tan LG. MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway. Oncol Rep. 2017; 38:1075–82. https://doi.org/10.3892/or.2017.5781.[PubMed]. Retraction in: Oncol Rep. 2022; 48:209. https://doi.org/10.3892/or.2022.8424.

[5] Pan T, Chen W, Yuan X, Shen J, Qin C, Wang L. miR-944 inhibits metastasis of gastric cancer by preventing the epithelial-mesenchymal transition via MACC1/Met/AKT signaling. FEBS Open Bio. 2017; 7:905–14. https://doi.org/10.1002/2211-5463.12215. [PubMed]. Retraction in: FEBS Open Bio. 2022; 12:2260. https://doi.org/10.1002/2211-5463.13512. 

[6] Sun XF, Sun JP, Hou HT, Li K, Liu X, Ge QX. MicroRNA-27b exerts an oncogenic function by targeting Fbxw7 in human hepatocellular carcinoma. Tumour Biol. 2016; 37:15325–32. https://doi.org/10.1007/s13277-016-5444-9.

[7] Liu X, Yang L, Tu J, Cai W, Zhang M, Shou Z, Yao Y, Xu Q. microRNA-526b servers as a prognostic factor and exhibits tumor suppressive property by targeting Sirtuin 7 in hepatocellular carcinoma. Oncotarget. 2017; 8:87737–49. https://doi.org/10.18632/oncotarget.21209.

[8] Wang X, Lin C, Zhao X, Liu A, Zhu J, Li X, Song L. Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Mol Cancer. 2014; 13:106. https://doi.org/10.1186/1476-4598-13-106.

[9] Tao Y, Han T, Zhang T, Ma C, Sun C. LncRNA CHRF-induced miR-489 loss promotes metastasis of colorectal cancer via TWIST1/EMT signaling pathway. Oncotarget. 2017; 8:36410–22. https://doi.org/10.18632/oncotarget.16850. 







参考信息

https://www.oncotarget.com/article/28702/




提供线索或对推文存在疑义,请联系邮箱:jxscuijian@163.com
微信搜一搜
 净研行动